E466

E466: Carboxymethylcellulose

Moderate concernFunction: thickener

What is E466?

E466 (Carboxymethylcellulose) is a thickener used in processed foods.

What the research says

A 2022 controlled trial in healthy people found it changed gut bacteria and their metabolites.

Regulatory status

European UnionApproved
United StatesApproved

Questions people ask

Is E466 (Carboxymethylcellulose) safe?

A 2022 controlled trial in healthy people found it changed gut bacteria and their metabolites.

Why is E466 added to food?

It is used as a thickener.

Does E466 make a food ultra-processed?

Yes. Under the NOVA system, cosmetic additives such as E466 mark a food as ultra-processed.

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